Grey’s Anatomy Star Eric Dane Reveals Battle With ALS

Eric Dane, widely known for his role as Dr. Mark Sloan on Grey’s Anatomy, revealed in April 2025 that he has been diagnosed with ALS (amyotrophic lateral sclerosis). The condition, also known as Lou Gehrig’s disease, affects the nervous system and leads to muscle weakness and loss of control. Dane shared that he has already lost the use of his right arm.

Despite this challenge, Dane continues to stay active in his career. In January 2025, he attended the premiere of the film Countdown. He appeared alongside co-stars and greeted fans warmly. Many praised his strength and courage for showing up during a difficult time. The public appearance marked one of his first since disclosing the diagnosis.

Dane said he is determined to keep working as long as possible. He confirmed plans to return to HBO’s Euphoria for its third season. He plays Cal Jacobs, a complex and pivotal character in the series. The show’s production team and cast have expressed strong support for Dane’s decision to keep acting.

Actor Jensen Ackles, who joined the Euphoria cast in its upcoming season, called Dane’s perseverance “resilience in its purest form.” He said working with Dane was inspiring and described him as focused and professional, even while facing personal health struggles.

ALS is a progressive disease. There is no known cure. Over time, it affects speaking, walking, and breathing. However, treatments can help manage symptoms and slow progression. Dane said he is receiving care from a team of specialists and is following a structured treatment plan.

In interviews, Dane has spoken about the emotional weight of the diagnosis. He admitted it was difficult to process at first. But with support from family, friends, and fans, he said he is trying to stay positive. He added that focusing on work and future projects gives him a sense of purpose.

Dane’s openness has helped raise awareness about ALS. Many fans shared messages of support, while health organizations thanked him for speaking publicly. His announcement has also led to increased interest in ALS research and fundraising efforts.

Colleagues from Grey’s Anatomy and Euphoria shared tributes on social media, praising Dane not only for his talent but also for his honesty and strength. They called him a valued friend and a respected actor who leads by example.

Though the road ahead is uncertain, Dane said he wants to keep doing what he loves for as long as he can. He hopes to bring attention to ALS while continuing to play roles that matter to him.

Eric Dane’s journey is a reminder of how quickly life can change, but also of how people can choose strength. His decision to stay in front of the camera, even during treatment, shows his deep commitment to storytelling and connection.

He remains a figure of courage, both on and off screen.